HR ↓ (Vital ↓)
Coaulopathy (PLT dysfunction)
Mydriasis (Catecholamine ↑)
Systemic hypothermia : 36℃ 미만
Core temperature측정 부위
esophagus, nasopharynx, tympanic membrane, pulmonary artery.
32-20℃ : 10℃ 하강에 metabolic oxygen demand 50% 감소. 1℃ 감소에 7%씩 감소.
15-18℃ : Total circulatory arrest.(up to 60min)
Hypothermia부작용
Reversible coagulopathy : PLT dysfunction, Thrombocytopenia.
Cardiac dysfunction : Bradycardia.
Left Hb-O2 saturation shift.
말초혈관 저항 증가
술 후 protein catabolism & stress response(→mydriasis)
Renal function 감소. 약물 대사 감소.
Poor wound healing.
Phase Ⅰ : vasodilation, 1-2℃감소/ 1st hour
Phase Ⅱ : 3-4 hour
Phase Ⅲ : equilibrium, hypothalamus 억제
Arrest 가능 : 성인 32-30℃, 소아 28-27℃